On the Printing of Rock Reliefs
January 1974
in “
Almogaren
”
hair follicle tissue engineering androgenetic alopecia co-flowing microfluidic-assisted technology growth factors dual aqueous microdroplets G/HAD microspheres glycosaminoglycan-based shells gelatin methacrylate cores mesenchymal cells mouse epidermal cells sustained growth factor release wet adhesion hair follicle regeneration hair loss hair regeneration tissue engineering
TLDR A new method shows promise for regenerating hair follicles to treat hair loss.
This study explored a novel method for hair follicle tissue engineering, which was promising for treating hair loss conditions like androgenetic alopecia. Researchers developed a co-flowing microfluidic-assisted technology to create dual aqueous microdroplets containing growth factors and double-layer cells for hair regeneration. They produced G/HAD microspheres using glycosaminoglycan-based shells and gelatin methacrylate cores to encapsulate mesenchymal and mouse epidermal cells. These microspheres showed favorable properties, such as sustained growth factor release and wet adhesion, and successfully induced hair follicle regeneration when transplanted into mice. The method allowed for the mass production of approximately 250 microspheres per minute, suggesting significant potential for improving hair regeneration techniques and applications in other tissue engineering fields.
