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This review discusses the multifaceted roles of regulatory T cells in cutaneous wound healing and highlights potential therapeutic strategies targeting these cells to enhance wound repair in chronic and diabetic wounds, but reports no new clinical results.

This review highlights the potential of wedelolactone from the plant Wedelia Chinensis, summarizing its reported pharmacological effects, including anti-inflammatory, antiviral, antibacterial, antitumor, anti-osteoporosis activities, and organ protection based on existing in vitro and in vivo research findings.

This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.

This review reports that the monosaccharide composition of polysaccharides significantly impacts their bioactivity, highlighting various roles for glucans, galactans, mannans, fructans, and pectin in immune regulation, antioxidant effects, and other biological functions.

In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.

This study observed that extracellular matrix scaffold membranes performed less effectively in wound healing for aged mice compared to younger ones, with senescent SPP1+ macrophages potentially hindering epidermal and fibroblast repair abilities.

This review summarizes Hibiscus rosa Sinensis's phytochemistry, pharmacology, and medicinal uses, noting various beneficial effects and the need for further research on its phytochemicals and clinical applications.

In this study, the combination of exercise and finasteride improved ovarian morphology and hormone levels in rats with polycystic ovary syndrome more effectively than either treatment alone.

This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.

In this review, the authors summarize the phytochemistry, pharmacology, and medicinal uses of Hibiscus rosa sinensis, highlighting its various benefits such as hypotensive and anti-inflammatory effects, while noting the need for more research on its specific mechanisms and potential toxicities.

This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.

This review examines the phytochemical constituents and pharmacological effects of licorice, discussing its potential health benefits and side effects without reporting new clinical results.

This review summarizes the major events and regulators of the hair cycle in mammals but reports no new experimental results; it emphasizes the complex regulation of stem cell activation and differentiation during hair growth.

This study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in human umbilical vein endothelial cells in vitro, with early pregnancy cells having a more significant effect.

This study observed that Epigallocatechin-3-gallate (EGCG) can inhibit phosphorylation of STAT1 and reduce a specific subset of immune cells in vitro and ex vivo, suggesting a potential role in maintaining immune privilege in alopecia areata.

This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.

This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.

This study found that a collagen patch made with fibroblast-derived extracellular matrix (fdECM) extracted from human lung fibroblasts enhanced wound healing by promoting wound contraction, angiogenesis, and skin remodeling in full-thickness skin wound models, including those with diabetic ulcers.

This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.

This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.

This paper provides a comprehensive review of melanocytes' roles in skin biology, focusing on their pigmentation and immune functions, and suggests potential research opportunities for preventing and treating skin disorders.

This study reviewed the role of inflammasomes in autoimmune skin diseases, highlighting their contribution to the pathogenesis of conditions such as vitiligo, alopecia areata, and psoriasis, and suggesting that targeting inflammasome dysregulation may offer new therapeutic options.

This review highlights the potential of targeting hepatic stellate cell ferroptosis as a treatment strategy for liver fibrosis, underscoring the need for further research into ferroptosis mechanisms in these cells to better understand and combat this condition.

In this study, researchers found that cytokine dysregulation linked to genetic background is present in both patients and healthy but genetically related individuals in two autoimmune skin diseases, Pemphigus vulgaris and Alopecia areata, suggesting that protective immune mechanisms may prevent disease manifestation in predisposed individuals.

Ancestry affects skin healing, with non-Hispanic Black patients showing more healing-related fibroblasts than White patients.

This article highlights that while cannabinoids show potential for treating various skin conditions, current evidence is largely preclinical, with a need for comprehensive clinical trials to confirm these promising effects.

This review found that different monosaccharide compositions in polysaccharides from 72 medicinal plants are linked to varying biological activities, with glucans, galactans, mannans, fructans, and pectins showing significant roles in immunomodulation, antioxidant effects, and other health benefits.

This review explores how various skin cell types contribute to photoaging driven by UV radiation, detailing their interactions and molecular mechanisms like oxidative stress and ECM degradation, ultimately offering insights for future anti-photoaging strategies.