Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling
June 2022
in “
Frontiers in bioengineering and biotechnology
”
decellularized extracellular matrix dECM fibroblasts COL-fdECM wound contraction angiogenesis epidermal barrier collagen hair follicles subepidermal nerve plexus skin remodeling diabetic ulcer fibroblast growth factors matrix metalloproteinases tissue inhibitors of metalloproteinases p38 signaling pathway ERK signaling pathway extracellular matrix ECM skin patch wound healing skin regeneration skin repair diabetic wound growth factors MMPs TIMPs p38 pathway ERK pathway
Studysummary This study found that a collagen patch made with fibroblast-derived extracellular matrix (fdECM) extracted from human lung fibroblasts enhanced wound healing by promoting wound contraction, angiogenesis, and skin remodeling in full-thickness skin wound models, including those with diabetic ulcers.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on frontiersin.org →