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This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This study found that platelet-rich plasma injections significantly improved olfactory function in patients with long-lasting postviral olfactory dysfunction, suggesting potential as a therapeutic strategy.

This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This source discusses the potential of topical JAK inhibitors, like tofacitinib, as effective treatments for autoimmune skin diseases, emphasizing their superior safety profile and minimal adverse effects compared to conventional systemic therapies.

This research discusses Stevens-Johnson syndrome and toxic epidermal necrolysis, life-threatening conditions often induced by immune-mediated drug reactions. Optimal management involves early diagnosis, drug withdrawal, and supportive therapy, though evidence for systemic treatments like corticosteroids and cyclosporin remains variable and lacks randomized controlled trial confirmation.

This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.

This study used a 3D bioprinted human lung cancer model in a mouse phantom to demonstrate a selective cytotoxic effect of X-rays on tumor cells, revealing differences from 2D cell models.

In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.

This study found that Aframomum melegueta seed extract improved wound healing in albino rats, with treated groups showing smaller wound sizes and formation of new tissues compared to controls.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

In this study, chronic zinc chloride administration in mice led to the replacement of long coarse hairs with short fine hairs, while overall skin histology remained normal.

In this study, ritlecitinib treatment for 12 and 24 weeks downregulated immunity-related genes and upregulated hair keratin genes in patients with alopecia areata, correlating with scalp hair regrowth response.

This review identifies several off-label uses of H-1 antihistamines in dermatology beyond itch and urticaria control, though the evidence is weak and further trials are needed.

This review highlights the potential medicinal benefits of Cuscuta reflexa, a parasitic plant known for its bioactive compounds, while emphasizing the need for further research to fully understand its therapeutic mechanisms and integrate its use into mainstream medicine.

3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.

This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.

In this study, topical naringin was found to significantly improve dermatitis severity and reduce inflammatory markers in a mouse model of atopic dermatitis, suggesting its potential as a therapeutic agent for this condition.

This article reviews the use of saw palmetto extract from a dermatologist's perspective, discussing its traditional role in treating androgenic alopecia and other androgen-related dermatological conditions, but it does not report specific research findings or results.

This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.

This review discusses recent advances in understanding and treating alopecia areata, emphasizing the ongoing challenges and unmet needs in disease management; it reports no new clinical findings.

This study found that exogenous melatonin improved cashmere fiber quality and yield in goats by enhancing antioxidant capacity and reducing pro-aging cytokine expression in secondary hair follicles.

This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.

This case report describes how unique endoscopic findings led to the diagnosis of Satoyoshi syndrome coexisting with systemic lupus erythematosus and gastric adenoma, expanding the endoscopic understanding of the syndrome.

In this study, researchers prepared a humanized CXCL12 antibody for alopecia areata treatment, finding it significantly delayed disease onset in mice and reduced immune cell activation, suggesting potential as an immune modulatory therapy.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.

This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.

This review summarizes the role of G-protein-coupled receptors in wound healing and reports no new clinical results, highlighting their importance in signaling pathways and recent discoveries in their functions.