Effectiveness of Platelet-Rich Plasma in Long-Lasting Post-Viral Olfactory Dysfunction: A Case Series

This study evaluated the effectiveness of platelet-rich plasma (PRP) in treating long-lasting postviral olfactory dysfunction (LPOD) in 43 patients, with an average age of 58.9 years and a mean dysfunction duration of 8.7 years. Patients received bilateral PRP injections, resulting in significant improvements in olfactory function, as indicated by an increase in the mean threshold, discrimination, and identification (TDI) score from 10.3 to 20.12, and a decrease in the olfactory disorder questionnaire (ODQ) score from 29.8 to 23.4 over 6 months. The study suggests PRP as a promising treatment for LPOD, though further controlled randomized trials are needed. Age was inversely associated with improvement in olfactory threshold scores.