Efficacy of Platelet-Rich Plasma Therapy in Oral Lichen Planus: A Systematic Review

    April 2023 in “ Medicina ”
    Shyamkumar Sriram, Shamimul Hasan, Abdullah Alqarni, Tanveer Alam, Sultan Mohammed Kaleem, Shahid Aziz, Humayoun Khan Durrani, Muhammed Ajmal, Ali Azhar Dawasaz, Shazina Saeed
    TLDR Platelet-rich plasma therapy improves oral lichen planus symptoms with few side effects.
    This systematic review evaluates the therapeutic potential of platelet-rich plasma (PRP) in treating oral lichen planus (OLP), an autoimmune disorder with no current cure. The review included five studies, which generally showed that PRP treatment significantly improved both objective and subjective symptoms of OLP, with efficacy comparable to standard corticosteroid treatments. Additionally, PRP therapy was associated with minimal adverse effects and recurrences. Despite these promising results, the review emphasizes the need for further research with larger sample sizes to confirm these findings.
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