March 2024 in “Journal of Society of Cosmetic Chemists of Japan” In this study, a medicated hair growth tonic containing RJ extract increased hair counts, the proportion of anagen phase hairs, and scalp moisture in human trials, although the specific role of RJ in hair growth remains unclear due to other active ingredients.
March 2024 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that minoxidil nanoparticles significantly increased hair growth in mice compared to commercial minoxidil and rosemary extract, demonstrating improved delivery and follicular uptake.
January 2024 in “Journal of Medicinal Food” This study found that Nephelium lappaceum extract restored hair growth more effectively than finasteride in mice with testosterone-inhibited hair growth, suggesting its potential as a nutraceutical for hair growth.
January 2024 in “Indian Journal of Pharmaceutical Sciences” In this laboratory study, researchers found that a methanol extract of peach kernel improved the growth and viability of human hair follicle dermal papilla cells, suggesting its potential efficacy for hair growth and care through cell proliferation and signaling pathways activation.
October 2023 in “Nutrients” This study suggests that a complex of millet and wheat extract may enhance hair health by reducing oxidative stress and inflammation and potentially prolonging the anagen phase of hair growth in models.
September 2023 in “Medicine” In this case report, a 41-year-old man with moderate androgenic alopecia showed an increase in hair density and improvements in hair characteristics after using Zimmer aqueous spray containing Zimmer herbal extract powder for 3 months, suggesting its potential as an alternative treatment for hair loss.
August 2023 in “Stem Cell Research & Therapy” This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
July 2023 in “International journal of research publications” In this study, topical application of 45% robusta green coffee bean extract in male wistar rats did not significantly enhance hair growth but effectively inhibited the increase of 5α-reductase type 1 levels when exposed to testosterone.
June 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, researchers found that high doses of rosemary extract given to lactating mother rats adversely affected their offspring, causing weight issues and damage to liver, kidney, and testis tissues, suggesting potential teratogenic risks if used during human pregnancy and lactation.
May 2023 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, young albino rats whose mothers received high doses of rosemary extract during lactation showed negative health effects, including inhibited weight gain and organ damage, suggesting potential teratogenicity of rosemary extract when used in such conditions.
May 2023 in “Frontiers in Pharmacology” Water extract of cacumen platycladi helps hair growth by affecting specific cell pathways.
This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
In this study, the combination of binahong leaf and lemongrass extracts was found to effectively inhibit the growth of the dandruff-causing fungus Pityrosporum ovale, with the strongest fungal growth inhibition observed at a 50% concentration of each extract.
In a study on hair loss treatment, researchers found that a serum containing Cinchona succirubra extract and caffeine improved hair density and reduced hair loss in individuals with acute telogen effluvium after 16 weeks of use, with significant improvements observable after just 4 weeks.
April 2023 in “Tikrit journal of pharmaceutical sciences” This pilot study found that ginger may improve hair growth and allow for a reduction in prednisolone dosage by mitigating oxidative stress in patients with alopecia areata over 60 days.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
April 2023 in “Biomedical Journal of Scientific and Technical Research” In this study, researchers observed that Indian head cactus extract significantly increased the proliferation of human follicle dermal papilla cells and induced the expression of hair growth-related genes, suggesting its potential as a new therapy for promoting hair growth.
April 2023 in “Journal of Investigative Dermatology” This study found that recombinant type III collagen may aid skin aging management by promoting fibroblast proliferation and migration, with a modest impact on inflammatory marker IL-6, though it did not significantly affect TNF-a secretion in vitro.
April 2023 in “Journal of Investigative Dermatology” In this clinical study, a serum containing Cinchona succirubra extract and Caffeine significantly improved hair growth and reduced hair loss in subjects with acute telogen effluvium.
This study found that an ethanolic extract of Ganoderma lucidum, especially at 15mg/kg, may promote hair growth in a rat model of testosterone-induced alopecia, showing effects comparable to minoxidil.
January 2023 in “Biocell” The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
December 2022 in “Journal of applied biological chemistry” In this study, Betula platyphylla extract, particularly fraction H3-2, promoted human derma papilla cell proliferation and increased expression of certain growth factors, suggesting potential benefits for hair loss prevention.
November 2022 in “Liberal Arts Innovation Center” In this study, spirulina extract was reported to exhibit antioxidant properties and enhance cell proliferation in dermal papilla cells, suggesting its potential for scalp protection and possibly reversing hair loss.
November 2022 in “Journal of Investigative Dermatology” This study suggests that applying a botanical extract targeting mechanosensory receptors improved well-being, oxytocin levels, and skin appearance in participants, unlike a placebo.
November 2022 in “Journal of Advances in Pharmacy Practices” This study found that a 5% concentration of terentang stem bark extract was the most effective in promoting hair growth in male rabbits.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
April 2022 in “Jurnal Penelitian Farmasi dan Herbal” In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.
March 2022 in “Journal of drug delivery and therapeutics” Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.