Administration of 45% Robusta Green Coffee Bean Ethanol Extract Solution and Its Effects on Hair Growth and 5α-Reductase Type 1 Levels in Male Wistar Rats

    July 2023 in “ International journal of research publications ”
    Kara Anindita, Anak Agung Gde Putra Wiraguna, Agus Eka Darwinata, Wimpie Pangkahila, Ni Wayan Winarti, I Made Winarsa Ruma
    Image of study
    TLDR Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
    The study investigated the effects of a 45% robusta green coffee bean ethanol extract solution on hair growth and 5α-reductase type 1 levels in 30 male Wistar rats. The rats were divided into three groups and exposed to topical testosterone and different treatments for 21 days. The results showed no significant difference in hair length growth between the groups, with the group treated with the coffee bean extract showing a mean hair length of 8.24 ± 0.899%. However, the level of 5α-reductase type 1, an enzyme linked to hair loss, was significantly lower in the group treated with the coffee bean extract (467.61 ± 101.82%) compared to the control group (700.95 ± 197.67%). The study concluded that while the coffee bean extract did not significantly increase hair growth, it was effective in inhibiting the increase of 5α-reductase type 1 levels.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 64 results

      community Temporalis Hypertrophy and hair loss

      in Treatment  24 upvotes 5 months ago
      Hair loss treatments include finasteride, minoxidil, and scalp exercises. Opinions vary on the effectiveness, with some attributing hair loss to muscle tension and inflammation, while others focus on genetics and DHT.

      community Unofficial Dermapen/Roller Guide

      in Treatment  254 upvotes 6 years ago
      Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

      community My Theory Of Androgenic Alopecia

      in Research/Science  19 upvotes 5 days ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Theory And Observation: Why Being Bald Can Really Work

      in Shaved/buzzed  88 upvotes 1 year ago
      The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

    Similar Research

    5 / 1000+ results