Complex Extract of Polygonatum Sibiricum and Nelumbinis Semen Improves Menopause Symptoms via Regulation of Estrogen Receptor Beta in an Ovariectomized Rat Model

    May 2023 in “ Nutrients ”
    Doori Park, Joo‐Heon Yoon, Boram Choi … In‐Hyuk Ha
    Studysummary This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
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    Research cited in this study 2

    1. Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats Frontiers in Neuroanatomy · 2022
    2. Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity Evidence-based Complementary and Alternative Medicine · 2021