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    GlossaryEstrogen Receptor Beta

    protein that binds estrogen and influences various biological processes

    Estrogen Receptor Beta (ERβ) is one of the two main types of receptors that bind to the hormone estrogen, the other being Estrogen Receptor Alpha (ERα). ERβ is involved in regulating various biological processes, including reproductive functions, bone density, and even hair growth. It plays a crucial role in mediating the effects of estrogen in different tissues, and its activity can influence conditions like alopecia, where hair loss occurs.

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  148 upvotes 2 days ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community The mechanism of androgenic alopecia

      in Research/Science  31 upvotes 2 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.