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    Glossary Estrogen Receptor Antagonist

    blocks estrogen from activating its cellular receptors

    An Estrogen Receptor Antagonist, also known as an Estrogen Blocker or ER Antagonist, is a substance that binds to estrogen receptors on cells and prevents estrogen from exerting its effects. This can be useful in treating conditions like hormone-sensitive cancers, such as certain types of breast cancer, by inhibiting the growth-promoting effects of estrogen on these cancer cells.

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    Research 10 of 1000+

    1. On the Effect of Estrogen Receptor Agonists and Antagonists on the Mouse Hair Follicle Cycle Journal of Investigative Dermatology · 1998 · 11 citations
    2. Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling Journal of Investigative Dermatology · 1998 · 8 citations
    3. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America · 1996 · 154 citations
    4. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway 2000 · 71 citations
    5. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    6. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling Endocrinology · 2005 · 92 citations
    7. Estrogen Receptor α, but not Estrogen Receptor β, is Involved in the Regulation of the Hair Follicle Cycling as well as the Thickness of Epidermis in Male Mice Journal of Investigative Dermatology · 2002 · 72 citations
    8. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons Chemosphere · 2017 · 10 citations
    9. Atherogenesis: Estrogen Induction of Polysialylated nCAM (PSA-nCAM) Blocks Monocyte Capture by Vascular Endothelial Cells ISGE series · 2019
    10. Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents Annals of Oncology · 2005 · 67 citations
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    Community 10 of 192

    1. Theaflavin (Black Tea Extract) reduce DHT, androgen receptor activity and estrogen Reddit · 20 Jul 2023
    2. If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit? Reddit · 6 Apr 2022
    3. High Estrogen causing hair loss? Reddit · 27 Aug 2023
    4. Long term finasteride users; Did you notice any improvement after 2 years? Reddit · 11 Apr 2023
    5. Stop expecting results in 2 months! Reddit · 5 May 2024
    6. Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years? Reddit · 4 Apr 2024
    7. Creatine's effect on Hair Loss and DHT Reddit · 3 Mar 2024
    8. Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others. Reddit · 18 May 2023
    9. Trying to understand finasteride side effects and post finasteride syndrome Reddit · 31 Oct 2020
    10. Why isn't anybody on topical bicalutamide? Reddit · 16 Jun 2024
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    Learn 2 of 5

    1. Estradiol Estrogen hormone, prescribed in tablet, patch and gel forms
    2. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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