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    GlossaryEstrogen Receptor Alpha

    protein inside cells that binds to estrogen hormone

    Estrogen Receptor Alpha (ERα) is a protein found inside cells that binds to the hormone estrogen. This receptor is crucial for regulating various biological processes, including reproductive functions and the development of certain tissues. In the context of hair and alopecia, ERα can influence hair growth and loss, as estrogen plays a role in the hair growth cycle.

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community Nandrolone Replacement Therapy

      in Treatment  42 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 1 week ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 2 years ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.