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Glossary Vaginal Dryness

reduced lubrication in vaginal tissues causing discomfort and pain

Vaginal dryness refers to a condition where the vaginal tissues are not adequately lubricated, often leading to discomfort, itching, and pain during intercourse. This can be caused by hormonal changes, particularly a decrease in estrogen levels during menopause, but can also result from certain medications, stress, or underlying health conditions. It is sometimes referred to as vaginal atrophy or atrophic vaginitis when it involves thinning and inflammation of the vaginal walls.

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Research

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research A Phase II Study of Vaginal Testosterone Cream (TEST) vs. Estring for Vaginal Dryness or Decreased Libido in Women with Early Stage Breast Cancer (BC) Treated with Aromatase Inhibitors (AIs).

9 citations , December 2009 in “Cancer Research”

This study concluded that both vaginal TEST and Estring may be effective for treating vaginal dryness in breast cancer patients on aromatase inhibitors, with adverse events being rare and manageable.

research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors

37 citations , September 2018 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.

research Histological and Gene Expression Analysis of the Effects of Menopause Status and Hormone Therapy on the Vaginal Introitus and Labia Majora

7 citations , January 2019 in “Journal of clinical medicine research”

This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.

research Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population

5 citations , September 2024 in “Maturitas”

In this study, an ultra-low dose combination of estradiol and dydrogesterone significantly reduced hot flushes and improved health-related quality of life among a multi-ethnic population of postmenopausal women, with no notable difference in serious adverse events compared to placebo.

research Treatment of female sexual dysfunction in postmenopausal women—What is the evidence?

2 citations , March 2004 in “Reviews in Gynaecological Practice”

This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.

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community Started OM and Fin one year ago

in Female 5 upvotes 3 months ago

The user is experiencing significant hair shedding despite using 1.25mg oral minoxidil and 1mg finasteride daily for a year. They are advised to monitor health factors like vitamin levels and heart health, and consider increasing ferritin levels for optimal hair growth.

community Attempting to assist people with gyno sides on finasteride

23 upvotes 2 years ago

Finasteride can cause gynecomastia due to hormonal imbalances. Management includes consulting an endocrinologist and using aromatase inhibitors like anastrozole or supplements like DIM and zinc.

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