In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.
May 2025 in “Indian Journal of Pharmacology” In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.
April 2025 in “International Journal of Advanced Research in Science Communication and Technology” This study developed a herbal shampoo using Reetha, Amla, Neem, Bringraj, Jatamanasi, and Aloe vera, reporting that the shampoo met pharmacognostical standards and showed increased hair growth activity, excellent washing and conditioning effects at 1% concentration, and stability with no skin irritation.
This study analyzed the phytochemical content of two Portulaca species and found that extracts from Portulaca oleracea L. and Portulaca grandiflora H. demonstrated suitable characteristics for hair tonic formulations, meeting Indonesian National Standards for cosmetic products.
April 2025 in “Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )” In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.
March 2025 in “PHARMADEMICA Jurnal Kefarmasian dan Gizi” This study evaluated cucumber extract shampoos and found they meet physical quality standards and exhibit strong antifungal activity against Candida albicans fungi, with efficacy increasing with higher concentrations of cucumber extract.
This study evaluated a hibiscus-based herbal shampoo formulation and found it to have effective cleansing and conditioning properties, mild antimicrobial benefits, and good physical stability, positioning it as a natural alternative to synthetic shampoos.
January 2025 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” This study focused on the formulation of topical gels containing Equisetum arvense extract, evaluating their consistency and preparation using gelling agents for potential application in enhancing drug delivery to wound sites.
This study examined the use of Purwaceng extract in shampoo formulations, concluding that a specific formula (Sample F1) showed good stability and safety, suggesting its potential effectiveness for hair health issues like dandruff and hair loss.
January 2025 in “International Journal of Endocrinology” This study found that the hydroalcoholic extract of the Dorema aucheri plant, especially at a 5% concentration, enhanced diabetic wound healing in male rats, improving re-epithelialization, collagen deposition, and neovascularization more effectively than other tested concentrations.
January 2025 in “Journal of Medicinal Food” This abstract mentions that while synthetic drugs like minoxidil and finasteride for androgenic alopecia have side effects, the characteristics of popular natural alternatives, such as soybean, remain largely unreported, despite consumer preference for these products.
January 2025 in “International Journal of Pharmacognosy and Pharmaceutical Research” This study found that hydroalcoholic extracts of Bacopa monnieri demonstrated significant antimitotic activity in an Allium cepa model, suggesting potential comparable effects to the standard drug methotrexate.
January 2025 in “Turkish Journal of Trauma and Emergency Surgery” This study found that administering Rosmarinus Officinalis extract peritoneally shortly after surgery may raise the risk of evisceration at the abdominal incision site.
December 2024 in “Proceeding International Collaborative Conference on Multidisciplinary Science” In this study, researchers developed a shampoo using ambon banana peel and green tea leaves, reporting that it showed positive characteristics and was safe for addressing hair loss, with optimal viscosity levels achieved in certain formulations.
December 2024 in “International Journal of Drug Delivery Technology” In this study, researchers developed and evaluated a topical dutasteride gel for treating male pattern baldness, finding that a formulation with 10% garlic extract showed the most promising results in promoting faster hair growth compared to other formulations tested.
December 2024 in “Jurnal Mandala Pharmacon Indonesia” In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.
November 2024 in “Traditional & Kampo Medicine” This study found that kumazasa extract promotes hair growth in a mouse model and human hair follicle cells, with effects similar to minoxidil, but it did not cause the inflammation observed with minoxidil use.
November 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study evaluated herbal hair gels made with extracts of flax seed and curry leaves, finding that the formulations offered good texture, stability, and sensory appeal while promoting healthy hair and scalp without irritation, making them suitable for regular use.
October 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the F6 formulation of a hair tonic containing EDS and ATG extracts produced the most significant hair growth in rabbits, without causing skin irritation and remaining stable throughout the observation period.
September 2024 in “Ahmar Metastasis Health Journal” In this study on Wistar rats, ginger and celery extracts at the tested dosage did not significantly affect hair growth onset, duration, or regrowth, nor did they cause significant inflammation, despite the presence of bioactive phytochemicals in the extracts.
August 2024 in “Cosmetics” This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.
August 2024 in “Majalah Obat Tradisional” This study found that microemulsions containing ethanol extract of cayenne pepper were effective in enhancing hair growth in rabbits, with the 0.2% concentration achieving the most significant results over a 30-day period, compared to a negative control.
July 2024 in “Journal of Investigative Dermatology” Propolis extract can promote hair growth and increase keratin production.
July 2024 in “Journal of Dermatological Treatment” In this case report, a 6-year-old boy with hidrotic ectodermal dysplasia 2 caused by GJB6 mutations showed no significant hair improvement with age, despite treatment with botanical extracts and Minoxidil.
July 2024 in “Natural Product Research” Nk-EE may help treat hair loss by promoting hair growth and preventing hair follicle damage.
June 2024 in “Deleted Journal” This study explored the effects of hair tonics made from a combination of kelor leaf and fragrant pandan leaf ethanol extracts on rat hair growth, finding that these combinations influenced hair growth when compared to single extract formulations over 28 days.
June 2024 in “The Open dermatology journal” In this study, researchers reported that an herbal extract with dihydroquercetin glucoside, epigallocatechin gallate glucoside, zinc, and glycine showed similar effectiveness and safety to minoxidil in treating androgenetic alopecia over 24 weeks, with no significant differences in hair growth outcomes between the groups.
May 2024 in “Journal of Agricultural and Food Chemistry” In a study using mice, researchers observed that Cacumen platycladi fermented with Lactiplantibacillus plantarum CCFM1348—both as postbiotics and synbiotics—promoted hair growth, potentially by engaging the Wnt/β-catenin signaling pathway and enhancing growth factor expression.
Ganoderma lucidum extract may help treat stress-related hair loss.
March 2024 in “Journal of Pharmaceutical and Sciences” This study investigated the phytochemical composition and antibacterial and antioxidant activities of Zaleya pentandra extracts, finding high total polyphenol and flavonoid content and significant antibacterial effects, particularly in acetone extract, which may be suitable for developing antibacterial agents.