Botanical Extract Combined with Minoxidil Improves Hidrotic Ectodermal Dysplasia Caused by p.G11R Mutations: A Case Report

    July 2024 in “ Journal of Dermatological Treatment ”
    Shiyi Zhong, Chuhan Huang, Mingyue Zhuang, Qingwu Liu, Zhao-hui Tian, Dingquan Yang
    Image of study
    TLDR Botanical extracts and Minoxidil improved hair condition in a boy with a genetic disorder.
    This case report details the treatment of a 6-year-old male with hidrotic ectodermal dysplasia 2 (HED2) due to a GJB6 (p.G11R) mutation, using botanical extracts combined with 5% minoxidil. The treatment led to significant hair growth after 1.5 months, suggesting it as a promising and safe strategy for congenital alopecia in children. The study emphasizes the psychological benefits of addressing hair issues in HED2 patients and notes the potential of botanical extracts in treating hair loss. Despite challenges like obtaining consent for trichograms, the report underscores the need for further research to understand the mechanism of the licorice extract used, offering valuable insights for future studies.
    Discuss this study in the Community →

    Research cited in this study

    12 / 12 results

    Related Community Posts Join

    6 / 23 results

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  13 upvotes 2 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 6 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  7 upvotes 5 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community Nice product I discovered, thought I would share.

      in Treatment  456 upvotes 10 months ago
      A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

      community Redensyl for Hair Loss — What It Can and Can’t Do

      in Treatment 2 months ago
      Redensyl is a plant-based treatment that may support hair regrowth by reactivating dormant follicles and improving hair density, especially in early-stage thinning. It is not a miracle cure and results vary; it is less proven than Minoxidil or Finasteride and may cause scalp irritation.

      community Is it worth using anti-hair loss shampoo?

      in Product  2 upvotes 1 week ago
      Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

    Related Research

    1 / 1 results