Botanical Extracts in Combination Improve Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Mutations

March 2022 in “ Journal of cosmetic dermatology ”

Baoquan Qu, Shengnan Meng, Chaowei Yang, Shuying Lv, Wenjun Lin, Dingquan Yang

botanical extracts autosomal recessive woolly hair hypotrichosis LIPH mutations hair growth prenatal diagnosis hair loss woolly hair

TLDR Botanical extracts can help treat hair loss in people with certain genetic conditions.

A study involving a 6-year-old female with autosomal recessive woolly hair (ARWH) caused by LIPH mutations demonstrated that a combined treatment of botanical extracts significantly improved hair growth. After 6 months, the patient's hair grew remarkably, and after 4 years, her hair remained dense. The study suggests that botanical extracts may offer a sustainable therapeutic effect for ARWH, although the specific mechanisms need further validation. The authors recommend considering regenerative strategies and prenatal diagnosis due to the significant impact of hair loss.

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Botanical Extracts in Combination Improve Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Mutations

Research cited in this study

research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

research Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

research Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia

research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia

research Assessment of a Bidirectional Association Between Major Depressive Disorder and Alopecia Areata

research Topical Minoxidil Improves Congenital Hypotrichosis Caused by LIPH Mutations

research Total Glucosides of Paeony Capsule Plus Compound Glycyrrhizin Tablets for the Treatment of Severe Alopecia Areata in Children: A Randomized Controlled Trial

research Congenital Hair Loss Disorders: Rare, But Not Too Rare

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