Botanical Extracts in Combination Improve Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Mutations

    March 2022 in “ Journal of cosmetic dermatology ”
    Baoquan Qu, Shengnan Meng, Chaowei Yang, Shuying Lv, Wenjun Lin, Dingquan Yang
    TLDR Botanical extracts can help treat hair loss in people with certain genetic conditions.
    A study involving a 6-year-old female with autosomal recessive woolly hair (ARWH) caused by LIPH mutations demonstrated that a combined treatment of botanical extracts significantly improved hair growth. After 6 months, the patient's hair grew remarkably, and after 4 years, her hair remained dense. The study suggests that botanical extracts may offer a sustainable therapeutic effect for ARWH, although the specific mechanisms need further validation. The authors recommend considering regenerative strategies and prenatal diagnosis due to the significant impact of hair loss.
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