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In this study, researchers observed that RE-ORGA, a preparation from Korean herbs, may help alleviate androgenic alopecia by promoting human dermal papilla cell proliferation, reducing 5α-reductase enzyme levels, and displaying anti-inflammatory properties, suggesting potential regulation of androgen receptor sensitivity.

This study found that the herbal extract HX109 promoted hair growth in mice by increasing cell viability and enhancing hair regrowth, with the effects increasing as doses rose.

This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.

This study found that Danthron induced apoptosis in a human malignant melanoma cell line through mitochondrial, endoplasmic reticulum, and death receptor pathways.

The study found that melatonin treatment in early postnatal cashmere goats increased both the quantity and quality of cashmere by promoting secondary hair follicle development and enhancing antioxidant enzyme activities.

This study found that topical formononetin treatment promoted hair regrowth in mice by normalizing hair follicle size and inhibiting apoptosis-related pathways.

This study found that sulforaphane and its related compounds may promote hair follicle growth in mice, suggesting their potential as treatment agents for androgenic alopecia.

In a mouse model, this study found that exposure to PM2.5 leads to significant postpartum hair loss, apparent via morphological changes and elevated markers of inflammation, apoptosis, and fibrosis, potentially exacerbated by changes in hormone receptors and stem cell populations.

In this study, finasteride reduced oxidative stress, apoptosis, and inflammation in liver, kidney, and testis tissues of diabetic rats while boosting antioxidants, indicating potential protective effects that require further human trials for clinical application.

Ginseng and Albizia extracts help prevent hair thinning with age.

This study found that Korean Red Ginseng may protect against chemotherapy-induced alopecia by reducing hair follicle damage in a human hair follicle organ culture model.

This study observed that overexpression of Bcl-2 in certain transgenic mice accelerates catagen progression and increases hair follicle apoptosis and alopecia, while Bcl-2 deficient mice show delayed hair growth and pigmentation changes.

In this study, Caizhixuan hair tonic was found to promote hair growth in androgenetic alopecia mice by regulating the PI3K/Akt and apoptosis pathways.

In this study, Salvia plebeia extract promoted hair growth by enhancing proliferation and anti-apoptotic effects in human dermal papilla cells and increased hair growth in treated mice.

This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.

This study investigated the effects of a YH complex, derived from Cinnamomum cassia and Astragalus membranaceus, on androgenetic alopecia in mice, finding that it promoted hair regrowth and improved hair follicle health by modulating hair cycle regulation and reducing apoptosis signaling pathways.

This study found that increased metastatic ability in colorectal cancer in a rat model was linked to changes in expression of multiple genes, including TGF-beta, PDGFb, and Rho B.

In a study using mice, researchers observed that Cacumen platycladi fermented with Lactiplantibacillus plantarum CCFM1348—both as postbiotics and synbiotics—promoted hair growth, potentially by engaging the Wnt/β-catenin signaling pathway and enhancing growth factor expression.

In this study, BCC therapy reduced oxidative stress and cell damage in cardiomyocyte cells, suggesting it may serve as a new treatment alternative for heart disease.

This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.

This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.

This study identified 14 genes affected by copy number variants that may contribute to alopecia areata, including four genes notably involved in autophagy and chromatin remodeling.

The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.

This study found that both androgenetic alopecia and alopecia areata showed significantly increased DKK-1 expression, potentially implicating it in the pathogenesis and as a treatment target for these conditions.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.

This study found that type I interferon response-related genes activated by RIG-1 and IL-17 pathways were significantly up-regulated in hair follicle and skin samples with chronic discoidal lupus erythematosus.

This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.

This review discusses the structure, expression, regulation, and potential roles of NcoA4 in cancer and other pathologies, reporting no new experimental findings.

This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.