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    The Effects of Finasteride on Apoptosis, Antioxidants, and Cytokines in Experimental Diabetic Rats

    June 2025 in “ Journal of Applied Toxicology ”
    Dilek Akşit, Eren Altun, Murat Çelebi … Hasan Akşit
    Studysummary In this study, finasteride reduced oxidative stress, apoptosis, and inflammation in liver, kidney, and testis tissues of diabetic rats while boosting antioxidants, indicating potential protective effects that require further human trials for clinical application.
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    Research cited in this study 6

    1. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
    2. Therapeutic Effect of Finasteride Through Its Antiandrogenic and Antioxidant Role in a Propionic Acid-Induced Autism Model: Demonstrated by Behavioral Tests, Histological Findings and MR Spectroscopy Neuroscience Letters · 2022
    3. Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells Pharmaceutics · 2021
    4. Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats The American Journal of the Medical Sciences · 2015
    5. 5α-Reductase Type 1 Deficiency or Inhibition Predisposes to Insulin Resistance, Hepatic Steatosis, and Liver Fibrosis in Rodents Diabetes · 2014
    6. Finasteride and Sexual Side Effects Indian Dermatology Online Journal · 2012

    Related research 1

    1. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003