Search

for
Search:

Did you mean Tumor Necrosis Factor Alpha?

Glossary Tumor Necrosis Factor Alpha

protein involved in inflammation and immune system regulation

Tumor Necrosis Factor Alpha (TNF-α) is a protein produced by the immune system that plays a crucial role in inflammation and the body's response to infection. It helps regulate immune cells, but excessive production of TNF-α is associated with chronic inflammatory diseases like rheumatoid arthritis and psoriasis.

Related Terms

Research

5 / 1000+ results

research Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.

79 citations , October 2003 in “PubMed”

In this study, PKCepsilon transgenic mice showed increased TNFalpha shedding during skin tumor promotion, which may contribute to the development of metastatic squamous cell carcinoma.

research Alopecia areata as another immune‐mediated disease developed in patients treated with tumour necrosis factor‐α blocker agents

61 citations , June 2010 in “Journal of the European Academy of Dermatology and Venereology”

This study highlights cases of alopecia areata that developed during anti-TNF-α therapy, suggesting a potential link or increased frequency, particularly among individuals with a personal or family history of autoimmune diseases.

research Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

53 citations , July 2009 in “Cancer Research”

In this mouse study, the researchers found that the monoclonal antibody ME1 causes hair follicle inflammation by up-regulating TNFα, which can be reduced by TNFα and interleukin-1 inhibitors.

research Tumor Necrosis Factor-Alpha and Polycystic Ovarian Syndrome: A Clinical, Biochemical, and Molecular Genetic Study

26 citations , August 2014 in “Genetic Testing and Molecular Biomarkers”

This study suggests that the TNF-α system may contribute to hyperandrogenism, obesity, and insulin resistance in polycystic ovarian syndrome, independent of the C850T polymorphism.

Alopecia Induced by Tumor Necrosis Factor-Alpha Antagonists: Description of 52 Cases and Disproportionality Analysis in a Nationwide Pharmacovigilance Database

research Alopecia induced by tumour necrosis factor-alpha antagonists: description of 52 cases and disproportionality analysis in a nationwide pharmacovigilance database

26 citations , March 2014 in “Rheumatology”

This study confirms an association between TNF-α antagonist exposure and alopecia, indicating a class effect among the medications examined.

View more "tumor necrosis factor-a" in research →

Community Join

1 / 1000+ results

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

View more "tumor necrosis factor-a" in community →

Learn

2 / 801 results

learn Stem Cell Factor

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

View more "tumor necrosis factor-a" in learn →

Clinics

6 / 13 results

All 13 clinic results →

Experts

2 / 2 results