Protective Effects of BCC Against Oxidative Stress in Cardiomyocyte Cells

    Bong-Geun Shin, Daekwan Kim
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    TLDR BCC can protect heart cells from damage caused by oxidative stress.
    The study found that Blood Cells Concentrate (BCC) can protect cardiomyocyte cells from oxidative stress induced by hydrogen peroxide (H₂O₂). BCC reduced oxidative stress and cell damage, lowered intracellular ROS levels, and suppressed apoptosis by decreasing cleaved caspase-9 and Bax protein expression. These results suggest that BCC, containing growth factors and CD34+ cells, may be a promising treatment for heart diseases caused by oxidative stress, though further research is needed to understand the mechanisms and standardize BCC preparation.
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