The Hair Growth-Promoting Effect of Rumex Japonicus Houtt. Extract
January 2016
in “
Evidence-based Complementary and Alternative Medicine
”
TLDR Rumex japonicus extract may promote hair growth more effectively than Minoxidil.
The document from January 1, 2016, describes a study on the hair growth-promoting effects of Rumex japonicus (RJ) Houtt. root extract. The study demonstrated that RJ extract induced antiapoptotic and proliferative effects on human dermal papilla cells (DPCs) and HaCaT cells, and promoted the anagen phase in a C57BL/6 mouse model. RJ treatment activated key cell proliferation signaling pathways, increased the Bcl-2/Bax ratio, and upregulated Ki-67 and ß-catenin expressions, which are associated with hair cell proliferation and hair growth. The effects of RJ were found to be stronger than those of Minoxidil, a known hair growth-promoting agent, in certain tests. These findings suggest RJ's potential as a therapeutic agent for hair growth, but the study calls for further research to identify active components and confirm efficacy through additional clinical trials. The number of participants or subjects in each experimental group was not specified, limiting the assessment of the study's strength based on sample size.
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