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This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.

In this study, a medicated hair growth tonic containing RJ extract increased hair counts, the proportion of anagen phase hairs, and scalp moisture in human trials, although the specific role of RJ in hair growth remains unclear due to other active ingredients.

This study found that the dietary supplement RJ-SP4AGA significantly improved hair growth and reduced hair loss in post-menopausal women with androgenetic alopecia over 16 weeks.

This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.

This study found that Rumex japonicus extract may help reduce symptoms of atopic dermatitis by inhibiting inflammatory responses in both cell cultures and a mouse model.