Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells

    January 2021 in “ iScience ”
    T. Fukuda, Kai Furuya, Kazumasa Takahashi … Tsuyoshi Ishii
    Studysummary Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
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    Research cited in this study 2

    1. Human-Derived Immortalized Dermal Papilla Cells With Constant Expression of Androgen Receptor Frontiers in Cell and Developmental Biology · 2020
    2. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007