1 citations
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April 2021 in “Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine” This study found that women with polycystic ovary syndrome in the Black Sea Region had higher levels of androgens, obesity, and insulin resistance, increasing their risk of metabolic syndrome compared to healthy women.
1 citations
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June 2018 in “International Journal of Contemporary Pediatrics” This study found that among children aged 1 to 5 with nutritional dermatoses, lower socioeconomic status and dietary fallacies were major factors contributing to poor nutritional status and skin issues.
June 2026 in “Quality in Sport” This narrative review analyzed the literature on premature hair graying, identifying potential contributors such as nutrient deficiencies, oxidative and emotional stress, smoking, genetic factors, autoimmune diseases, and medication side effects, but reported no effective treatment to reverse it, underscoring the necessity for further research.
May 2026 in “International Journal of Creative and Open Research in Engineering and Management” This review reports that nutritional and lifestyle factors, such as micronutrient deficiencies and stress, play a significant role in hair health and loss, but emphasizes that evidence for interventions remains limited and more research is needed to establish clear clinical guidelines.
March 2026 in “Obesity Surgery” This study found that hair loss after metabolic and bariatric surgery peaks at 3 months and improves by 6 months, with iron deficiency and female sex being strong predictors of hair loss.
January 2026 in “Dermatology Practical & Conceptual” In this study, pediatric alopecia areata was associated with higher rates of vitiligo, asthma, and ADHD, and significantly lower levels of vitamin B12, ferritin, and TSH compared to healthy controls, highlighting the need for comprehensive evaluation.
December 2025 in “International Journal of Innovative Technologies in Social Science” This review examines how lifestyle factors like diet, smoking, and stress may influence alopecia areata, but concludes that current evidence is inconsistent and largely observational, urging further research.
October 2025 in “Diseases” This study reports that women with hair loss had significantly lower levels of several biomarkers, including hemoglobin, iron, copper, selenium, vitamin D, vitamin B12, folate, and thyroid hormones, compared to healthy controls.
September 2025 in “Online Türk Sağlık Bilimleri Dergisi” This study observed that pediatric patients with diffuse, non-scarring alopecia had significantly lower levels of zinc and folate compared to matched healthy controls, suggesting a possible link between these deficiencies and hair loss in children.
August 2025 in “International Journal for Vitamin and Nutrition Research” This review highlights the important role of the vitamin B complex in enhancing tissue repair, reducing inflammation, and improving surgical outcomes in plastic and reconstructive procedures by supporting cellular processes such as mitochondrial efficiency, neurotransmitter biosynthesis, and wound healing pathways.
July 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This case report documented a 20-year-old male with alopecia areata who experienced slight hair regrowth following treatment with cyclosporine and methylprednisolone, highlighting the importance of individualized treatment plans and consideration of medication side effects.
This study observed that premature hair graying was more prevalent among obese individuals, those with vitamin B12 and D deficiencies, smokers, and people with high stress, regardless of whether they were medical or non-medical students at a university in Saudi Arabia.
July 2024 in “Brazilian Journal of Clinical Medicine and Review” This review found that hair loss is common in women after bariatric surgery, linked to nutritional deficiencies and rapid weight loss, highlighting the need for further research and nutrient monitoring.
July 2024 in “Medical alphabet” In this review, researchers discuss the factors contributing to early graying, such as genetic predisposition, oxidative stress imbalance, and nutrient deficiencies, and highlight potential restoration methods involving palmitoyl tetrapeptide-20 and the endocannabinoid system in hair follicles.
In this study, researchers found a strong association between premature graying of hair and deficiencies in vitamin D and B12, hypothyroidism, and deranged iron profiles, along with higher stress, altered appetite, smoking, and sleep pattern issues, significantly impacting quality of life.
June 2023 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This study demonstrated that derivatives of dehydroepiandrosterone (2a-b, 3a-f, and 4a-f) significantly reduced viable LNCaP prostate cancer cells, suggesting potential therapeutic use for metastatic prostate cancer, while finasteride did not alter cell viability.
June 2023 in “JAAD international” This report highlights that 49.4% of U.S. patients with skin issues use complementary and alternative medicine (CAM), with 6% leveraging it specifically for their skin conditions, including treatments like herbal, vitamin, and mineral supplementation for alopecia.
October 2022 in “Research, Society and Development” This review highlights that while vitamin and mineral supplementation shows limited impact on hair loss treatment, deficiencies in iron, zinc, and vitamin D are common among patients with telogen effluvium.
January 2022 in “Indian journal of paediatric dermatology” In this study, patients with premature graying of hair had lower levels of zinc, magnesium, and Vitamin B12 compared to healthy controls.
January 2021 in “Turkiye Klinikleri Journal of Dermatology” This study found that male patients with hair loss often had lower levels of vitamins D and B12, suggesting these deficiencies should be tested for in treatment evaluations.
January 2019 in “Springer eBooks” Combination therapies might work better for some vitiligo patients, but results vary.
July 2018 in “International journal of clinical & experimental dermatology” This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.
April 2012 in “Cancer research” In this study, the authors found that targeting mTORC1 with rapamycin inhibited TPA-induced skin tumor promotion by affecting keratinocyte proliferation, including critical stem cell populations in the mouse epidermis.
17 citations
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December 2013 in “Dermatologic Surgery” This study found that autologous noncultured epidermal suspension transplantation improved leukotrichia in 88.1% of treated vitiligo lesions without significant adverse events.
14 citations
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June 2016 in “PubMed” This study found that patients with vitiligo commonly had facial involvement and associated autoimmune thyroid disease, highlighting the importance of monitoring thyroid antibodies and regular follow-up.
9 citations
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September 2020 in “Journal of cosmetic dermatology” This case report describes koebnerization-induced vitiligo in a woman following repeated eyebrow microblading, suggesting a link between the procedure and the phenomenon in susceptible individuals.
7 citations
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July 2020 in “Dermatologic therapy” This review discusses premature graying of hair, highlighting risk factors like smoking and vitamin deficiencies, and suggests that addressing underlying conditions may reverse the graying process.
2 citations
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September 2024 in “Journal of Bioscience and Applied Research/Journal of Bioscience and Applied Research ” This study found that vitamin D, calcium, iron, and ferritin significantly correlate with alopecia in both genders, while zinc, B12, folic acid, and TSH correlate only in males.
1 citations
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January 2024 in “Pediatric Dermatology” In this case study, a 12-year-old boy with a restricted diet exhibited symptoms of scurvy, including leg weakness and bruising, which improved following treatment with vitamin C and B12 supplements, highlighting the impact of severe vitamin deficiencies on health.
September 2026 in “European Journal Pharmaceutical and Medical Research” This source discusses premature greying of hair, often linked to lifestyle, stress, and nutritional deficiencies, and notes mainstream dermatology focuses on dietary supplements, while homeopathy offers a holistic approach for treatment.