September 2026 in “European Journal Pharmaceutical and Medical Research” This source discusses the various causes of premature greying of hair, highlighting lifestyle, genetic factors, and nutritional deficiencies, and contrasts mainstream dermatology's focus on nutritional supplementation with homeopathy's holistic treatment approach for long-term management.
June 2026 in “International Journal of Homoeopathic Sciences” In this case report, a 22-year-old female with recurrent alopecia totalis experienced progressive hair regrowth and scalp health normalization over eight months following individualized homeopathic treatment and nutritional support.
In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.
April 2026 in “Global Journal of Health Science” This study observed that patients with hypothyroidism-associated hair loss commonly have deficiencies in several vitamins and minerals, suggesting that these deficiencies may be linked to their condition.
January 2026 in “CyberLeninK (CyberLeninka)” In this study, researchers found that combining advanced physiotherapy and specialized dermacosmetics in patients with androgenetic alopecia significantly improved metabolic markers, increasing serum zinc, copper, folic acid, and vitamin D levels more than standard treatments.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the causes and management of premature greying in children, noting it may indicate underlying health issues, and emphasizes structured evaluations and treatments, particularly for nutritional deficiencies and hypothyroidism, to address hair depigmentation.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights concerns around premature greying in children, detailing possible links to nutritional deficiencies and other health issues, and emphasizes that structured evaluation and targeted treatment may aid in reversing the condition.
November 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review reported that premature greying in children, which can indicate certain deficiencies or disorders, may be addressed through a structured evaluation and treatment targeting factors like vitamin B12 and iron deficiencies or hypothyroidism, providing a practical approach for pediatric care.
September 2025 in “Cutaneous and Ocular Toxicology” In this study, researchers found no significant differences in serum levels of ferritin, folate, vitamin B12, vitamin D, or thyroid function between patients with scarring alopecia and healthy controls, suggesting these factors may not play a major role in the disease's pathogenesis.
July 2025 in “ALEXMED ePosters” In this study, the researchers aimed to evaluate the levels of substance P, folic acid, and ferritin in the serum of female patients experiencing hair fall and trichodynia.
June 2025 in “British Journal of Dermatology” This study investigated premature greying and found lower levels of vitamin D and vitamin B12 in affected individuals compared to controls, associating micronutrient deficiencies with altered hair pigmentation, though no significant link between micronutrient deficiencies and inflammatory markers was observed.
February 2025 in “Journal of Cosmetic Dermatology” In this study, researchers observed that deficiency in biochemical markers, notably ferritin and serum iron, is frequently found in female patients diagnosed with telogen effluvium, suggesting these tests are crucial in understanding and treating the condition.
October 2024 in “Journal of the Pakistan Medical Association” This letter discusses the various risk factors associated with premature greying of hair, highlighting genetic predispositions, nutritional deficiencies, stress, and lifestyle factors, while noting a lack of conclusive data on effective interventions, as detailed in the reviewed studies.
May 2024 in “Our Dermatology Online” In this case report, a mother and daughter with celiac disease experienced hair loss as their primary or initial extraintestinal symptom, highlighting the potential link between celiac disease and alopecia.
July 2023 in “Dermatology practical & conceptual” In this study, hemoglobin levels were the only marker positively correlated with anagen hair ratios in patients with telogen effluvium, suggesting it may be a cost-effective initial test for management.
This study found a significant association between premature greying of hair and deficiencies in vitamin D, vitamin B12, hypothyroidism, and disrupted iron profiles, alongside lifestyle factors like stress and smoking.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, patients who underwent Roux-en-Y gastric bypass surgery lost significant weight and improved obesity-related complications, but experienced increased hair loss and needed careful calcium and protein management.
March 2022 in “IP Indian journal of clinical and experimental dermatology” This study found that ferritin and cobalamin levels were better indicators than hemoglobin in assessing chronic nonscarring hair loss in females of reproductive age.
March 2020 in “The Thai Journal of Veterinary Medicine” This case report describes the occurrence of juvenile diabetes mellitus with concurrent exocrine pancreatic insufficiency in a Thai Bangkaew dog, highlighting its successful management with insulin, pancreatic enzymes, and methylcobalamin.
October 2019 in “Postgraduate Medical Journal” This case report describes a patient with pellagrous dermatitis related to chronic alcoholism, whose symptoms resolved within two weeks following treatment with nicotinamide, vitamin B12, and thiamine.
January 2009 in “International Journal of Trichology” Dr. Shyam B Verma encourages more scientific research on hair disorders and criticizes the unscientific hair care market in India.
September 2006 in “Baghdad Science Journal” This study suggests a link between hair loss experienced during pregnancy and lactation and inadequate daily intake of certain nutrients.
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June 2017 in “Asian journal of beauty & cosmetology” In this study, Rosa multiflora root extracts showed strong antioxidant activity and promoted expression of growth factors IGF1 and PDGFB, suggesting potential use as a natural hair growth agent.
113 citations
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June 2015 in “Stem Cell Research & Therapy” This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.
32 citations
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December 2000 in “Phytomedicine” In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.
120 citations
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July 2005 in “Dermatologic surgery” This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in aging facial skin over 12 weeks.
15 citations
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February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” This study concludes that egg shell membrane hydrolysates, particularly Fraction I, may effectively mitigate UV-B radiation-induced wrinkles and promote skin collagen and hyaluronic acid production, suggesting potential use in functional cosmetics.
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December 2023 in “Aktualʹnì problemi sučasnoï medicini” This study found that immunohistochemical markers like ER, PgR, b-catenin, p21, and Ki-67 showed significant expression changes after progesterone therapy in women with endometrial hyperplasia without atypia, suggesting their potential as diagnostic and prognostic markers.
279 citations
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June 1990 in “Journal of Clinical Oncology” The study found that for positive-node breast cancer patients aged 50 and older, adding chemotherapy to tamoxifen significantly improved disease-free survival compared to tamoxifen alone.
38 citations
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September 2011 in “PLOS ONE” This study found that activin B promotes epithelial wound healing in mice through the RhoA-Rock-JNK-cJun signaling pathway, suggesting a potential therapeutic role for activin B in wound repair.