Medical Therapies

January 2019 in “ Springer eBooks ”

Alain Taı̈eb

1,25-dihydroxyvitamin D3 analogues systemic steroids antioxidants immunosuppressive drugs phototherapy PUVA narrowband UVB oral corticosteroids methotrexate anti-interferon therapies vitamins B12 folic acid Janus kinase inhibitors vitamin D3 analogues steroids UVB therapy corticosteroids JAK inhibitors

TLDR Combination therapies might work better for some vitiligo patients, but results vary.

The document reviewed various medical therapies for vitiligo, including both established and emerging treatments. It discussed the efficacy of treatments like 1,25-dihydroxyvitamin D3 analogues, systemic steroids, antioxidants, and immunosuppressive drugs. Combination therapies with phototherapy methods such as PUVA and narrowband UVB showed mixed results, with some studies indicating enhanced repigmentation and others finding no additional benefit. The document also covered the potential roles of oral corticosteroids, methotrexate, anti-interferon therapies, vitamins B12, folic acid, and Janus kinase inhibitors. Overall, the findings suggested that combination therapies might offer better outcomes for some patients, but results varied across studies.

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research Treatment of Vitiligo with the Topical Janus Kinase Inhibitor Ruxolitinib: A 32-Week Open-Label Extension Study with Optional Narrow-Band Ultraviolet B

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