Evaluation of Metabolic and Hormonal Parameters in Women with PCOS Living in the Black Sea Region

    April 2021 in “ Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine ”
    Nur Dokuzeylül Güngör, Samettin Çelik, Mehmet Güçlü, Sebahattin Çelik, Ferhat Cengiz
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    TLDR Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.
    This study compared 109 women with PCOS to 91 healthy controls in the Black Sea region, revealing that women with PCOS had higher levels of fasting blood glucose, fasting insulin, HOMA-IR, total cholesterol, LDL-C, and triglycerides, and lower HDL-C levels, indicating a higher risk of cardiovascular diseases and insulin resistance. Additionally, PCOS patients had lower vitamin D and B12 levels. The study concluded that PCOS patients have an increased risk of metabolic syndrome due to high androgen levels, obesity, and insulin resistance, emphasizing the need for lifestyle changes and effective diagnosis and treatment to prevent diabetes and cardiovascular diseases.
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