Repigmentation of Leukotrichia Due to Retrograde Migration of Melanocytes After Noncultured Epidermal Suspension Transplantation

The study evaluated the improvement of leukotrichia in vitiligo patients using a modified procedure of autologous noncultured epidermal suspension transplantation. It included 31 individuals with stable vitiligo, treating 42 lesions with leukotrichia. The procedure involved preparing an autologous noncultured epidermal suspension from a split skin graft and transplanting it to a dermabraded recipient area. Patients received methylcobalamin and were advised on daily sun exposure. Over a follow-up period of 6 months to 1 year, 88.1% of the treated lesions showed improvement, with body hair showing faster improvement than pubic, facial, and scalp hair. No significant adverse events were reported. This study was notable for being the first with a large number of patients using this transplantation method for leukotrichia in vitiligo.