Repigmentation of Leukotrichia Due to Retrograde Migration of Melanocytes After Noncultured Epidermal Suspension Transplantation
December 2013
in “
Dermatologic Surgery
”
TLDR The treatment improved hair color in most vitiligo patients without major side effects.
The study retrospectively evaluated the improvement of leukotrichia in 31 individuals with stable vitiligo, treating 42 lesions using a modified autologous noncultured epidermal suspension transplantation. The procedure involved preparing an epidermal suspension from a split skin graft and transplanting it to a dermabraded area, followed by methylcobalamin administration and sun exposure. Over a follow-up period of 6 months to 1 year, 88.1% of the treated lesions showed improvement, with body hair responding faster than pubic, facial, and scalp hair. No significant adverse events were reported, marking this as the first study with a large patient group using this transplantation method for leukotrichia improvement.