TLDR New vitiligo treatments focus on controlling immune damage and restoring skin color.
A global consensus led to a new classification protocol for vitiligo, identifying the absence of functioning melanocytes in lesions and the presence of CD4+ and CD8+ T lymphocytes at the lesion edges. Treatments aimed to control autoimmune damage and stimulate melanocyte migration from unaffected areas to affected skin, with a combination of physical, pharmacological, and surgical methods.
281 citations,
January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
532 citations,
September 2011 in “Journal of the American Academy of Dermatology” Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
May 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
240 citations,
May 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
