Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits

In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.

In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.

This paper offers a detailed overview of B vitamins, detailing their importance for energy, cognition, and metabolism, conditions leading to their deficiencies, symptoms of deficiencies, and the foods rich in these essential nutrients.

In this study, researchers found that biotin levels increase with age but not gender, and there is a notable negative relationship between biotin levels and triglyceride levels, suggesting biotin should be checked in patients with high triglyceride levels.

In this randomized controlled trial, PRP combined with redensyl, saw palmetto, and biotin showed superior efficacy in improving androgenetic alopecia grading scores in male patients when compared to PRP with Procapil.

In this case study, a 25-year-old female with premature hair graying achieved over 90% conversion of gray hair to black hair after 5 months of treatment with a topical peptide solution and hair supplements.

In this case report, a young adult male with resistant alopecia areata showed nearly 90% hair regrowth after 3 months of treatment with tofacitinib, alongside biotin supplementation, without any side effects observed.

This study found that microbial adenosine and biotin treatments derived from Staphylococcus epidermidis Cicaria culture may help inhibit hair loss by maintaining the hair's growth phase.

This study found that a 6-week treatment with both brands of biotin and dexpanthenol significantly improved hair fall count and hair density in people with diffuse pattern hair loss, with no significant difference between the two brands.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.

This study found that temporary hair loss is common after laparoscopic sleeve gastrectomy, and biotin supplementation showed low effectiveness in preventing this hair loss.

This study found that male androgenetic alopecia patients had significantly lower serum zinc levels and suboptimal biotin levels compared to healthy controls, suggesting the potential value of zinc and biotin supplementation.

This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.

This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.

This case report suggests that poor hair and nail growth in children with autism spectrum disorder and developmental delay may indicate a biotin-responsive condition, as biotin and acetazolamide therapy improved symptoms and school performance in the reported patient.

In this letter, excessive hair loss due to telogen effluvium was observed as a distressing side effect in the early months of valproate treatment, potentially linked to disruption in biotin metabolism, although the exact mechanism remains unclear.

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in aging facial skin over 12 weeks.