Efficacy of Intramuscular Injections of Biotin and Dexpanthenol in the Treatment of Diffuse Hair Loss: A Randomized, Double-Blind Controlled Study Comparing Two Brands

    July 2022 in “ Dermatologic Therapy ”
    Aniseh Samadi, Yasaman Ketabi, Rojin Firooz, Alireza Firooz
    Image of study
    TLDR Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.
    The study compared the efficacy of two brands of biotin and dexpanthenol in treating diffuse hair loss over a 6-week period. Fifty patients (41 women and 9 men) with diffuse pattern hair loss were randomized to receive weekly injections of dexpanthenol and biotin, manufactured by either Pars Behvarzan or Bayer Company. Hair fall count and total hair density significantly improved in both groups one and eight weeks after the last treatment session (p-value <0.01 for hair fall count and 0.04 and 0.02, for hair density in Pars and Bayer groups, respectively). The only significant difference between the two groups was an improvement in the terminal/vellus hair ratio in the Bayer group in both follow-up visits, compared to the Pars group (p-value = 0.02 and 0.033 for weeks one and eight). The study concluded that a 6-week treatment with both brands of biotin and dexpanthenol was effective and safe for people with diffuse pattern hair loss.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 1000+ results

      community Suspicious about my dermatologist

      in Product  10 upvotes 4 months ago
      A 17-year-old is concerned about hair loss and questions his dermatologist's advice against using finasteride due to age. The dermatologist recommended a serum with aloe vera, saw palmetto, biotin, and dexpanthenol, but the user is skeptical and considers using minoxidil instead.

      community What should I expect from dutasteride?

      in Finasteride/Dutasteride  2 upvotes 3 years ago
      The user tried Minoxidil, PRP, Hair Carboxytherapy, and topical Dutasteride with limited success and is now on oral Dutasteride. They are experiencing some hair loss reduction but no significant density improvement, leading to feelings of depression.

      community biotin leads to acne and sebum on scalp ??

      in Finasteride/Dutasteride  1 upvotes 6 months ago
      User is experiencing increased sebum, dandruff, and acne after taking a supplement containing biotin, iron, zinc, and calcium pantothenate along with finasteride. They are questioning if biotin is the cause and whether they should stop taking it.

      community Have you tried Biotin supplements for your hair?

      in Product  25 upvotes 11 months ago
      People shared that Biotin supplements did not improve their hair loss and some experienced stronger nails or more pimples. They suggested trying finasteride or minoxidil instead for hair loss treatment.

      community Reminder: Biotin supplementation is a scam.

      in Product  112 upvotes 1 year ago
      Biotin supplements are considered ineffective for hair loss and are not supported by evidence. People in the conversation have mixed experiences, with some noting benefits for nails and skin but not hair, while others continue to use biotin as part of their vitamin regimen.

    Related Research

    5 / 5 results