Staphylococcus Epidermidis Cicaria, a Novel Strain Derived From the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss

The study evaluated Staphylococcus epidermidis Cicaria, a novel strain from the human microbiome, as a treatment for hair loss. Analysis of scalp microbiomes from 42 participants (21 with hair loss and 21 without) revealed that Cicaria promotes hair growth by increasing epidermal cell growth factors and vasodilator genes, showing similar efficacy to Minoxidil but without adverse effects. Clinical trials using a Cicaria-based shampoo demonstrated increased microbial diversity, improved hair follicle length, and root diameter. Active components, adenosine and biotin, were identified as key contributors. The findings suggest Cicaria as a promising and cost-effective alternative treatment for hair loss, supported by both in vitro and clinical evidence.