Quantification of Biotin in Plasma Samples by Column Switching Liquid Chromatography – Tandem Mass Spectrometry
January 2021
in “
Scandinavian journal of clinical and laboratory investigation
”
Studysummary This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.
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