research Meeting Report: The 15th Annual Meeting of the European Hair Research Society
The conference highlighted new diagnostic tools, the role of genetics in hair loss, and emerging treatments.
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research Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Genesis of Androgenic Alopecia in Women of Childbearing Potential
Certain gene variations and irregular X chromosome activity may contribute to hair loss in women who can have children.
research Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Pathogenesis of Androgenic Alopecia
Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.
research Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Electrical Stimulation to Human Dermal Papilla Cells for Hair Regenerative Medicine
Electric stimulation can increase hair growth by activating certain genes in skin cells.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Genome-Wide Expression Profile Analysis of 3D Cultured Dermal Papilla Cells from Patients with Androgenic Alopecia
Hair loss in androgenic alopecia patients is linked to changes in certain genes that control cell growth and death.
research URB Expression in Human Dermal Papilla Cells
The gene URB is more active in human hair growth cells and responds to a hair-related hormone.
research Fructus Psoraleae Treating Androgenetic Alopecia Through 5-Alpha Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Healthy Males and Females in an Open Label Pilot Study
Ageratum conyzoides L. extract may effectively and safely treat hair loss.
research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Urtica Dioica Extract Downregulates the Gene Expression of 5α-Reductase Type II in HaCaT Cells: Possible Implications Against Androgenic Skin Diseases
Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.
research A Synonymous Polymorphism of APCDD1 Affects Translation Efficacy and Is Associated with Androgenic Alopecia
A specific gene change in APCDD1 increases the risk of hair loss.
research Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells
The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research MRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
research Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract
The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research Hypoxia Inducible Factor-1a Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells
A protein called HIF-1a helps control hair growth genes and could be targeted to treat hair loss.
research Black Phosphorus Nanosheets Encapsulated Microneedle for Multifunctional Therapy for Androgenic Alopecia
A new treatment using microneedles with black phosphorus and laser helps regrow hair effectively and safely.
research The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination With Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study
Combining stem cell-conditioned media with anti-androgen drugs can improve hair growth in male pattern baldness.
research Vitamin D Increases Expression of Cathelicidin in Cultured Sebocytes
Vitamin D boosts a specific protein in skin cells linked to hair follicles.
research Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
research Expression of Signal Transducer and Activator of Transcription-3 in Androgenetic Alopecia: A Case Control Study
Higher STAT3 levels are found in hair loss areas, but not linked to hair loss severity.
research Application of LncRNA-miRNA-mRNA CeRNA Network Analysis in the Treatment of Androgenic Alopecia
The lncRNA LOXL1-AS1 may help diagnose and treat androgenic alopecia.
research Brassica Oleracea Extract, Glucosinolates, And Sulforaphane Promote Hair Growth In Vitro And Ex Vivo
Brassica oleracea extract, glucosinlates, and sulforaphane can boost hair growth and might be used to treat hair loss.
research Osteopontin Gene Is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction
Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.