The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination With Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study

    November 2023 in “ PubMed ”
    Majid Kamali-Dolat Abadi, Gholamhossein Yousefi, Farzaneh Dehghani … Mehdi Dianatpour
    Studysummary In this study using animal models, umbilical cord stem cell conditioned media combined with oral anti-androgens improved hair regeneration in androgenetic alopecia, enhancing hair follicle cycles and reducing inflammation, suggesting potential as a promising therapy.
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    Research cited in this study 20

    1. Androgenetic Alopecia: Therapy Update Drugs · 2023
    2. Trichoscopic Evaluation of Dental Pulp Stem Cell Conditioned Media for Androgenic Alopecia PubMed · 2023
    3. Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review Cells · 2023
    4. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    5. Conditioned Media-Integrated Microneedles for Hair Regeneration Through Perifollicular Angiogenesis Journal of Controlled Release · 2022
    6. Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia Pharmaceutics · 2022
    7. Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle Stem Cell Research & Therapy · 2021
    8. Wharton's Jelly-Derived Mesenchymal Stem Cells in the Treatment of Four Patients with Alopecia Areata Advances in Clinical and Experimental Medicine · 2021
    9. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells · 2020
    10. Shikimic Acid, a Mannose Bioisostere, Promotes Hair Growth with the Induction of Anagen Hair Cycle. Scientific Reports · 2019
    11. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors to Improve Skin Regeneration ACS Applied Bio Materials · 2019
    12. Getting to the Core of the Dermal Papilla Journal of Investigative Dermatology · 2017
    13. Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications PubMed · 2017
    14. Androgenetic Alopecia: A Review Endocrine · 2017
    15. Adipose-Derived Stromal Cells in Regenerative Medicine: A Review World Journal of Stem Cells · 2017
    16. Hair-Growth Stimulation by Conditioned Medium from Vitamin D3-Activated Preadipocytes in C57BL/6 Mice Life sciences · 2015
    17. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    18. Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth Scientific Reports · 2014
    19. Human Wharton's Jelly Stem Cells and Their Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds Journal of Cellular Biochemistry · 2013
    20. New Topical Antiandrogenic Formulations Can Stimulate Hair Growth in Human Bald Scalp Grafted Onto Mice International Journal of Pharmaceutics · 2000

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