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research Down-regulation of genes related to photoaging and inflammation in UVBirradiated mice premature skin photoaging by linoleic acid-rich tempeh oil

1 citations , June 2019 in “Food Research”

In this study, tempeh oil rich in PUFAs, particularly from black soybean, significantly down-regulated MMP-9 gene expression in UVB-irradiated mice skin, indicating potential for use in preventing skin photoaging.

research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq

8 citations , December 2017 in “Skin appendage disorders”

This study observed that the genes WNT7A, CASP7, and TNF were overexpressed in early stages of androgenetic alopecia, suggesting involvement of the WNT pathway, apoptosis, and inflammation in the disorder's development.

research Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation

August 2025 in “BMC Pharmacology and Toxicology”

The LTF gene may help predict and manage nonspecific orbital inflammation.

research Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances

7 citations , January 2022 in “Plants”

This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.

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Community Join

5 / 965 results

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

131 upvotes 1 year ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community What else can make hair more sensitive to DHT?

17 upvotes 1 month ago

Genetics, inflammation, poor scalp circulation, stress, thyroid issues, low iron, vitamin D deficiency, steroids, age, fungal infections, stress, and creatine can increase hair sensitivity to DHT. Treatments mentioned include dutasteride, minoxidil, and Kre Alkalyn Monohydrate.

community 18M: Thinning at 17, Hair Loss Concern on Back and Sides, Inflammation Question

in General 83 upvotes 1 year ago

An 18-year-old noticed hair thinning at 17, started finasteride 5 months ago, and saw shedding stop but no regrowth. They suspect male pattern baldness due to family history and are concerned about thinning on the back and sides, possibly due to inflammation.

community I have a theory about hair loss

in Treatment 8 months ago

Hair loss is often linked to inflammation and DHT, with treatments like finasteride, dutasteride, and minoxidil being effective for many. Natural remedies like turmeric and oils are discussed, but medications are generally seen as more reliable for managing genetic hair loss.

community Is Ketoconazole a big factor in preventing hairloss?

in Ketoconazole 41 upvotes 1 year ago

Ketoconazole shampoo may help with scalp health and inflammation but is not a substitute for DHT blockers like finasteride. It is generally considered a minor addition to hair loss treatment, with varying opinions on its effectiveness.

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Learn

9 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn sh-Polypeptide-7

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Epidermal Growth Factor

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Omega 3

Did you know omega-3 can lower scalp inflammation that leads to sudden hair loss? Omega-3 can reduce scalp inflammation, potentially preventing sudden hair loss.
Does omega-3 help with scalp inflammation or irritation linked to conditions like dandruff or alopecia? Omega-3 may help reduce scalp inflammation linked to dandruff and alopecia.

learn Ginkgo biloba

Can ginkgo biloba reduce scalp inflammation that contributes to hair loss? Ginkgo biloba may help reduce scalp inflammation, potentially benefiting hair loss.

learn Hydrocortisone

Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

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Experts

1 / 6 results

Hair System Specialist
Jane Genesi
Marlton, PA, United States

Clinics

6 / 68 results

All 68 clinic results →

Jane Genesi