Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis

    July 2018 in “ General and comparative endocrinology ”
    Diana E.K. Campbell, Valérie S. Langlois
    Studysummary This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.
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    Research cited in this study 4

    1. Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride General and Comparative Endocrinology · 2014
    2. Expression Profiles of Reproduction and Thyroid Hormone Related Transcripts in the Brains of Chemically Induced Intersex Frogs Sexual Development · 2011
    3. Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development General and Comparative Endocrinology · 2009
    4. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana Tropicalis Sexual Development · 2009