115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
13 citations
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July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
24 citations
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January 2011 in “Sexual Development” The study investigated the effects of endocrine-disrupting chemicals, specifically finasteride and fadrozole, on the brain mRNA levels of the frog species Silurana tropicalis. It was found that finasteride-induced intersex frogs exhibited higher mRNA levels of several genes related to sex steroids and thyroid hormones, such as aromatase, estrogen receptor α, thyroid hormone receptor β, and deiodinase type 3, compared to control males and females. Additionally, these intersex frogs showed increased mRNA levels of androgen receptor and estrogen receptor β. In contrast, fadrozole did not affect the brain gene expression but reduced aromatase activity. The study concluded that intersex conditions, whether induced by anti-androgen or anti-estrogen treatments, resulted in distinct transcript profiles in the brain, highlighting a complex relationship between thyroid hormone-responsive genes and androgen status in frogs.
61 citations
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May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
60 citations
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November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.