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    Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses

    February 2019 in “ Toxicological Sciences
    Camilla Schwartz, Anne Marie Vinggaard, Sofie Christiansen … Terje Svingen
    Studysummary This study reports that chemically induced short anogenital distance in male rat fetuses involved distinctive transcriptional changes, suggesting roles for estrogen and Wnt2 signaling in anogenital tissue development.
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    Research cited in this study 3

    1. Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats Toxicological Sciences · 2003
    2. Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor Toxicology and Applied Pharmacology · 1993
    3. External Genitalia Abnormalities in Male Rats Exposed In Utero to Finasteride, a 5α-Reductase Inhibitor Teratology · 1990

    Related research 2

    1. Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses Toxicological Sciences · 2019
    2. Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats Toxicological Sciences · 2003