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research External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor

122 citations , July 1990 in “Teratology”

This study found that oral administration of finasteride to pregnant rats caused dosage-related developmental toxicities, including hypospadias and decreased anogenital distance in male offspring.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations , March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

research Keloids in male genitalia—Systematic review and illustrative case report

3 citations , February 2024 in “Wound Repair and Regeneration”

In this systematic review, researchers examined the occurrence and treatment of penile keloids and found that circumcision is a common trigger, particularly in prepubescent children. Despite various therapeutic approaches, penile keloids are rare, complicating further study of this condition.

research Genitalia, Male The effect of finasteride on spermatogenesis of Mesocricetus auratus 1 Impacto da finasterida na espermatogênese do Mesocricetus auratus

January 2008

This study found that finasteride treatment in adult hamsters led to significant testicular alterations and reduced spermatogenesis compared to untreated controls.

research Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism

46 citations , December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology”

In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.

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Community Join

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community Male (24) Using Dutasteride Since 2020 – Concerns About Having Kids

in Finasteride/Dutasteride 90 upvotes 1 year ago

A 24-year-old male using dutasteride for hair loss is worried about its effects on fertility and future children's health. Users advise consulting a doctor, possibly switching to finasteride, or stopping dutasteride before conception due to its impact on sperm count.

community 6 months on treatment nw7. Male 29 y

in Progress Pictures 300 upvotes 1 year ago

A 29-year-old male shares his hair loss treatment progress using dutasteride, minoxidil, dermastamping, and ketoconazole shampoo, while discontinuing RU58841 due to side effects. He is hopeful for hair recovery to consider a hair transplant and discusses potential side effects and experiences with other users.

community Spironolactone topically with a try ?!

in Research/Science 1 upvotes 2 years ago

A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

2264 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

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Learn

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learn Hair Transplant

What causes male pattern baldness? Male pattern baldness is caused by genetic sensitivity to the hormone DHT.
What is male pattern baldness? Male pattern baldness is a genetic condition causing hair loss in men, starting with a receding hairline.
Can male pattern baldness be prevented? Male pattern baldness cannot be completely prevented, but treatments can slow its progression.

learn Nanoxidil

Can Nanoxidil help with both male and female pattern baldness? Nanoxidil may help with both male and female pattern baldness, but lacks FDA approval.

learn Pumpkin seed oil

How does pumpkin seed oil help block DHT, the hormone linked to male and female pattern baldness? Pumpkin seed oil may help block DHT, potentially reducing hair loss.

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