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GlossaryAnogenital Distance

distance between the anus and genitals

Anogenital Distance (AGD) is the measurement from the anus to the base of the genitals. It is a marker of prenatal androgen exposure and is often used in medical and biological research to assess reproductive health and development. In males, a longer AGD is typically observed compared to females, and variations in AGD can be linked to certain health conditions and endocrine disruptions.

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research Presence of Polycystic Ovary Syndrome Is Associated with Longer Anogenital Distance in Adult Mediterranean Women

42 citations , August 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

research Polycystic Ovary Syndrome Is Associated With Anogenital Distance, A Marker Of Prenatal Androgen Exposure

32 citations , February 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

research Assessment of Anogenital Distance as a Diagnostic Tool in Polycystic Ovary Syndrome

15 citations , October 2018 in “Reproductive Biomedicine Online”

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

research Anogenital Distance as a Biomarker for Incomplete Masculinization: Molecular Mechanisms in the Perineum

January 2020 in “Research Portal Denmark”

A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.

research Effects of Finasteride and DEHP on Anogenital Distance and Nipple Retention After Perinatal Exposure in Rats

1 citations , January 2005 in “Research Portal (King's College London)”

Finasteride and DEHP exposure during development can change reproductive markers in rats.

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