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GlossaryAnogenital Distance

distance between the anus and genitals

Anogenital Distance (AGD) is the measurement from the anus to the base of the genitals. It is a marker of prenatal androgen exposure and is often used in medical and biological research to assess reproductive health and development. In males, a longer AGD is typically observed compared to females, and variations in AGD can be linked to certain health conditions and endocrine disruptions.

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research Presence of Polycystic Ovary Syndrome Is Associated with Longer Anogenital Distance in Adult Mediterranean Women

42 citations , August 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

research Polycystic Ovary Syndrome Is Associated With Anogenital Distance, A Marker Of Prenatal Androgen Exposure

32 citations , February 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

research Assessment of Anogenital Distance as a Diagnostic Tool in Polycystic Ovary Syndrome

15 citations , October 2018 in “Reproductive Biomedicine Online”

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

research Effects of Finasteride and DEHP on Anogenital Distance and Nipple Retention After Perinatal Exposure in Rats

1 citations , January 2005 in “Research Portal (King's College London)”

Finasteride and DEHP exposure during development can change reproductive markers in rats.

research Anogenital Distance as a Biomarker for Incomplete Masculinization: Molecular Mechanisms in the Perineum

January 2020 in “Research Portal Denmark”

A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.

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