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A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgens may block hair growth signals, targeting this could treat hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Effective PCOS treatments require targeting specific signaling pathways.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Human keratinocytes do not naturally respond to androgens.

Finasteride may improve prostate cancer treatment outcomes.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.