Estrogen and Androgen Signaling in the Pathogenesis of Benign Prostatic Hyperplasia

    January 2011 in “ Nature reviews. Urology ”
    Clement Ho, Fouad K. Habib
    Studysummary Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
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    Research cited in this study 4

    1. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2004
    2. Clinical Use of 5α-Reductase Inhibitors Cambridge University Press eBooks · 2001
    3. Natural Potent Androgens: Lessons from Human Genetic Models Baillière s Clinical Endocrinology and Metabolism · 1998
    4. Role of 5α-Reductase in Health and Disease Baillière's clinical endocrinology and metabolism · 1994