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GlossaryAdipose-Derived Stem Cell-Conditioned Medium (ADSC-CM)

solution with growth factors from fat-derived stem cells

Adipose-Derived Stem Cell-Conditioned Medium (ADSC-CM) is a solution that contains various growth factors, cytokines, and other bioactive molecules secreted by adipose-derived stem cells (stem cells taken from fat tissue). This medium is used in regenerative medicine and cosmetic applications, including treatments for hair loss, as it promotes cell growth, healing, and tissue regeneration.

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research Adipose Tissue-Derived Stromal Vascular Fraction in Regenerative Medicine: A Brief Review on Biology and Translation

316 citations, June 2017 in “Stem Cell Research & Therapy”

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

research Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

March 2023 in “Cells”

Stem cell treatments show promise for hair loss but need more research.

research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth

76 citations, August 2018 in “International Journal of Cosmetic Science”

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

research Platelet-Rich Plasma: Applications in Cosmetic Medicine and Surgery

1 citations, June 2018 in “Advances in Cosmetic Surgery”

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.

Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/Beta-Catenin Pathway

research Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/Beta-Catenin Pathway

September 2023 in “Stem Cells International”

Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.

research The Latest Advance in Hair Regeneration Therapy Using Proteins Secreted by Adipose-Derived Stem Cells

28 citations, December 2012 in “The American Journal of Cosmetic Surgery”

Proteins from stem cells improved hair growth in patients with hair loss.

research Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration

19 citations, June 2021 in “Tissue Engineering and Regenerative Medicine”

Fat stem cell particles help regrow hair.

research Adipose-Derived Stem Cell-Based Therapies for Male/Female Pattern Hair Loss

1 citations, January 2016 in “Journal of stem cell research and medicine”

Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.

research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study

83 citations, March 2015 in “International Journal of Dermatology”

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

Bioinspired Engineering of ADSC Nanovesicles in Thermosensitive Hydrogel to Enhance Autophagy of Dermal Papilla Cells for Androgenetic Alopecia Treatment

research Bioinspired Engineering of ADSC Nanovesicles in Thermosensitive Hydrogel to Enhance Autophagy of Dermal Papilla Cells for Androgenetic Alopecia Treatment

March 2024 in “Bioactive Materials”

New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.

research The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)

19 citations, January 2017 in “Stem Cells International”

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.

research Efficacy of Adipocytes Derived Stem Cells Conditioned Media (ADSC-CM) in Management of Androgenetic Alopecia: A Review

January 2021 in “European Journal of Molecular & Clinical Medicine”

research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin, and MIP-1α in the Adipose-Derived Stem Cell Secretome in Androgenetic Alopecia

1 citations, February 2022 in “Experimental Dermatology”

Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.

Autologous Adipose-Derived Stem Cell Versus Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: Efficacy, Side Effects, and Safety

research Autologous Adipose-Derived Stem Cell Versus Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: Efficacy, Side Effects, and Safety

2 citations, January 2018 in “Journal of clinical & experimental dermatology research”

Both fat-derived stem cells and platelet-rich plasma are effective and safe for hair loss, but stem cells give better results with more side effects.

Efficacy of Platelet-Rich Plasma Versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study

research Efficacy of Platelet-Rich Plasma Versus Mesotherapy with Recombinant Growth Factors and Stem Cell-Conditioned Media in Androgenetic Alopecia: A Retrospective Study

June 2024 in “Skin Appendage Disorders”

Both PRP and MZT treatments can significantly improve hair growth in patients with androgenetic alopecia.

research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury

8 citations, January 2022 in “Burns and trauma”

Skin cell-derived vesicles can help heal skin injuries effectively.

research Therapeutic Potential of Stem Cells in Follicle Regeneration

45 citations, August 2018 in “Stem Cells International”

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

research Autologous Adipose Transplantation: An Effective Method to Treat Alopecia After Trauma - A Case Report

9 citations, September 2019 in “Clinical, Cosmetic and Investigational Dermatology”

Using a patient's own fat tissue helped treat hair loss caused by an injury.

research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia

4 citations, March 2022 in “Pharmaceutics”

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

research Infranatant Portion of Microfragmented Adipose Tissue: A Promising Source of Stromal Vascular Fraction for the Management of Androgenetic Alopecia

February 2021 in “International journal of regenerative medicine”

A new method using fat tissue cells may help treat hair loss.

research Regenerative Medicine Applications in Dermatology and Aesthetics

2 citations, June 2022 in “Cosmoderma”

Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.

research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

62 citations, October 2017 in “JAMA facial plastic surgery”

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

research Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers

12 citations, June 2023 in “International Journal of Molecular Sciences”

Innovative biomaterials show promise in healing chronic diabetic foot ulcers.

research An Advanced Review: Polyurethane-Related Dressings for Skin Wound Repair

1 citations, November 2023 in “Polymers”

Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.

research Cell and Cell-Free Therapies in Osteoarthritis

10 citations, November 2021 in “Biomedicines”

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.