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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Dutasteride is more efficient than finasteride, but individual results vary.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Muscles can make their own androgens, which may help muscle growth.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.

Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Treat hair loss in postmenopausal women with diet, avoiding certain drugs, and using medications like minoxidil or finasteride.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Early onset hair loss linked to genetics and androgen levels.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.