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    Glossary 3D cell culture

    technique growing cells in three dimensions for realistic conditions

    3D cell culture is a technique used to grow cells in an environment that more closely mimics the natural conditions inside the human body compared to traditional two-dimensional (2D) cultures. By allowing cells to interact in all three dimensions, this method provides a more accurate representation of how cells behave, grow, and respond to treatments, making it particularly valuable for research in areas like cancer, tissue engineering, and drug development.

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    Research 30 of 1000+

    1. Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles Experimental Dermatology · 2017 · 55 citations
    2. In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers Scientific Reports · 2017 · 14 citations
    3. Poor Capability of 3D-Cultured Adipose-Derived Stem Cells to Induce Hair Follicles in Contrast to 3D-Cultured Dermal Papilla Cells Annals of Dermatology · 2016 · 10 citations
    4. RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture Journal of Cellular and Molecular Medicine · 2020 · 6 citations
    5. Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis Burns and trauma · 2023 · 1 citations
    6. 854 CCL5 affects the hair-inductive capacity of three-dimensional (3D)-cultured dermal papilla cells Journal of Investigative Dermatology · 2017 · 1 citations
    7. 600 Differential Molecular Signature of Dermal Papilla Cells (DPCs) from Balding and Non balding Scalp in 2D, 3D culture and Co-culture with Adipose-derived stem cells (ASCs) Journal of Investigative Dermatology · 2019
    8. 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance Journal of Investigative Dermatology · 2016
    9. 1324 Impairment of hair-inducing capacity of 3D-cultured human dermal papilla cells by the ablation of STAT5 Journal of Investigative Dermatology · 2018
    10. Genome-wide expression profile analysis of 3D cultured dermal papilla cells from patients with androgenic alopecia Chinese Journal of Dermatology · 2014
    11. Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures Proceedings of the National Academy of Sciences · 2019 · 67 citations
    12. Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy Stem Cell Research & Therapy · 2020 · 48 citations
    13. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture Tissue engineering. Part A · 2014 · 46 citations
    14. Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold Biomolecules · 2020 · 29 citations
    15. 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing Stem Cell Research & Therapy · 2020 · 17 citations
    16. Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures Cell Proliferation · 2019 · 16 citations
    17. 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects iScience · 2024 · 13 citations
    18. 3D cell culture stimulates the secretion of in vivo like extracellular vesicles bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 5 citations
    19. Comparative analysis of 3D and 2D cell-culturing methods in hair follicle spheroid morphogenesis and drug responsiveness Biomaterials Advances · 2025 · 1 citations
    20. High-throughput screening of 3D co-culture hair follicle mimetic tissue with enhanced ECM for the screening of hair growth promoting compounds Biomaterials Research · 2024
    21. 3D Co-Culture model of Endothelial Colony Forming Cells (ECFCs) Reverses Late Passage Adipose-derived Stem Cell Senescence for Wound Healing Research Square (Research Square) · 2020
    22. New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes Reproductive Biology and Endocrinology · 2022 · 13 citations
    23. Mimicking fat grafting of fibrotic scars using 3D‐organotypic skin cultures Experimental Dermatology · 2023 · 4 citations
    24. Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth Frontiers in Cell and Developmental Biology · 2021 · 5 citations
    25. In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models Frontiers in Bioengineering and Biotechnology · 2023
    26. Generation of functionally active resident macrophages from adipose tissue by 3D cultures Frontiers in Immunology · 2024 · 2 citations
    27. Bioinspired tuning of glycol chitosan for 3D cell culture NPG Asia Materials · 2016 · 61 citations
    28. New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes Research Square (Research Square) · 2022
    29. Disease-related biomarkers as experimental endpoints in 3D skin culture models Cytotechnology · 2023 · 3 citations
    30. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture Cell · 2018 · 249 citations