Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia

    January 2021 in “ Social Science Research Network ”
    Paula Martins de Oliveira, Thuany Alencar‐Silva, Felipe Q. Pires … Juliana Lott Carvalho
    Studysummary This study suggests that a nanostructured lipid carrier formulation of minoxidil and latanoprost may effectively target hair follicles and enhance drug penetration for alopecia treatment.
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    Research cited in this study 22

    1. Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence Clinical, Cosmetic and Investigational Dermatology · 2021
    2. The Influence of Sebaceous Content on the Performance of Nanosystems Designed for the Treatment of Follicular Diseases Journal of Drug Delivery Science and Technology · 2020
    3. Simultaneous Determination of Minoxidil and Minoxidil Sulfate by High-Performance Liquid Chromatography with UV Detection and Its Applications Medicine in Drug Discovery · 2020
    4. LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin Journal of Pharmaceutical and Biomedical Analysis · 2020
    5. Effect of Physical Stimuli on Hair Follicle Deposition of Clobetasol-Loaded Lipid Nanocarriers Scientific Reports · 2020
    6. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    7. Off-Label Use of Topical Minoxidil in Alopecia: A Review American Journal of Clinical Dermatology · 2019
    8. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
    9. Nanotechnology Advances for Hair Loss Therapeutic Delivery · 2018
    10. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    11. Minoxidil-Encapsulated Poly(L-Lactide-Co-Glycolide) Nanoparticles with Hair Follicle Delivery Properties Prepared Using Solvent Evaporation and Sonication Bio-medical Materials and Engineering · 2018
    12. Use of Minoxidil Sulfate Versus Minoxidil Base in Androgenetic Alopecia Treatment: Friend or Foe? Skin appendage disorders · 2018
    13. Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase International Journal of Molecular Sciences · 2017
    14. Selective Delivery of Adapalene to the Human Hair Follicle Under Finite Dose Conditions Using Polymeric Micelle Nanocarriers Nanoscale · 2017
    15. Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery European Journal of Pharmaceutical Sciences · 2016
    16. Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells Nanomedicine: Nanotechnology, Biology and Medicine · 2015
    17. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    18. Penetration Enhancer-Containing Vesicles as Carriers for Cutaneous Delivery of Minoxidil: In Vitro Evaluation of Drug Permeation by Infrared Spectroscopy Pharmaceutical Development and Technology · 2012
    19. Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil International Journal of Pharmaceutics · 2011
    20. Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model Experimental dermatology · 2005
    21. Development and Characterization of Minoxidil-Loaded Liposomal System for Delivery to Pilosebaceous Units Journal of Liposome Research · 2004
    22. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002

    Related research 6

    1. Comparison of Efficacy, Safety, and Satisfaction of Latanoprost Versus Minoxidil, Betamethasone, and in Combination in Patients with Alopecia Areata: A Blinded Multiple Group Randomized Controlled Trial Dermatologic Therapy · 2022
    2. Latanoprost and Minoxidil: Comparative Double-Blind, Placebo-Controlled Study for the Treatment of Hair Loss Surgical and Cosmetic Dermatology · 2018
    3. Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata Journal of The American Academy of Dermatology · 2005
    4. Contact Dermatitis Caused By Topical Minoxidil: Case Reports And Review Of The Literature Dermatitis · 1991
    5. Topical Minoxidil in the Treatment of Alopecia Areata Plastic & Reconstructive Surgery · 1985
    6. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984