3 citations
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December 2000 in “International Journal of Cosmetic Science” This study established that a human epidermal model can be utilized to assess 5alpha-reductase activity and evaluate enzyme modulators, such as finasteride, for dermatological applications.
April 2016 in “Journal of Investigative Dermatology” This study found that secreted factors from skin-derived precursors, especially those pre-treated with jasmine extract, enhanced keratinocyte growth and influenced reconstructed human epidermis thickness in lab experiments.
18 citations
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
April 2019 in “Journal of Investigative Dermatology” This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.
August 1993 in “Journal of Dermatological Science”