The Influence of Sebaceous Content on the Performance of Nanosystems Designed for the Treatment of Follicular Diseases

    July 2020 in “ Journal of Drug Delivery Science and Technology ”
    Seila Tolentino, Maíra N. Pereira, Mikaella C. de Sousa … Tais Gratieri
    Studysummary This study found that while a nanostructured lipid carrier improved drug delivery in conventional skin models, excess sebaceous content hindered its effectiveness in targeting hair follicles.
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    Research cited in this study 11

    1. Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery European Journal of Pharmaceutical Sciences · 2016
    2. Minoxidil Topical Treatment May Be More Efficient If Applied on Damp Scalp Compared to Dry Scalp Dermatologic Therapy · 2016
    3. Hidradenitis Suppurativa/Acne Inversa: An Endocrine Skin Disorder? Reviews in endocrine and metabolic disorders · 2016
    4. Hair Follicles as a Target Structure for Nanoparticles Journal of innovative optical health sciences/Journal of innovation in optical health science · 2015
    5. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    6. Self-Assembled Polymeric Nanocarriers for the Targeted Delivery of Retinoic Acid to the Hair Follicle Nanoscale · 2015
    7. Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia Journal of Pharmaceutical Sciences · 2013
    8. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
    9. Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate Journal of Microencapsulation · 2011
    10. Investigation of the Penetration and Storage of a Shampoo Formulation Containing Caffeine into the Hair Follicles by In Vivo Laser Scanning Microscopy Laser Physics Letters · 2007
    11. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006

    Related research 2

    1. Hair Disorders Springer eBooks · 2018
    2. Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland Experimental Dermatology · 2018