Effective Topical Delivery of Minoxidil via Chitosan Coated Nanocapsules to Remodel Microenvironment of Dermal Follicle for Hair Regeneration

    February 2026 in “ Drug Delivery and Translational Research ”
    Jin Sil Lee, Tae Eon Park, Panmo Son … Won Il Choi
    Studysummary Chitosan-coated nanocapsules improve minoxidil delivery for better hair regrowth.
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    Research cited in this study 23

    1. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025
    2. Temperature-Responsive Detachable Microneedles Integrated with Minoxidil Nanoparticle for Effectively Promoting Hair Regrowth Chemical Engineering Journal · 2024
    3. Chitosan and Its Amphiphilic Derivative Nanoparticles Loaded with Minoxidil for Induction of Hair Growth: In Vitro and In Vivo Evaluation International Journal of Biological Macromolecules · 2023
    4. Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management Journal of Drug Delivery Science and Technology · 2023
    5. The Preparation of High Minoxidil Loaded Transfersomes and Its Gel for Effective Topical Treatment of Alopecia Journal of Drug Delivery Science and Technology · 2023
    6. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    7. Development of Minoxidil-Loaded Double Emulsion PLGA Nanoparticles for the Treatment of Hair Loss Journal of Industrial and Engineering Chemistry · 2022
    8. Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules International Journal of Molecular Sciences · 2022
    9. Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration Applied Materials Today · 2020
    10. Novel Iron Oxide Nanocarriers Loading Finasteride or Dutasteride: Enhanced Skin Penetration for Topical Treatment of Alopecia International Journal of Pharmaceutics · 2020
    11. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    12. Transdermal Delivery of Minoxidil Using HA-PLGA Nanoparticles for the Treatment of Alopecia Biomaterials Research · 2019
    13. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    14. Psychological Assessment in 355 Chinese College Students With Androgenetic Alopecia Medicine · 2018
    15. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    16. Drug Discovery for Alopecia: Gone Today, Hair Tomorrow Expert Opinion on Drug Discovery · 2015
    17. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    18. Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in Mouse Skin Skin pharmacology and physiology · 2015
    19. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    20. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    21. Human Hair Follicles Contain Two Forms of ATP-Sensitive Potassium Channels, Only One Sensitive to Minoxidil The FASEB Journal · 2008
    22. The Hair Growth Promoting Effect of Sophora Flavescens Extract and Its Molecular Regulation Journal of Dermatological Science · 2002
    23. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998